Dead Rush is the end of the world as we know it, as seen through the eyes of one man - David (David Michael Moote), as he takes us through his journey: before, during and after the zombie apocalypse.

During a late night taping of Dr. Nasty's Cavalcade of Horror, bloody chaos takes place while screening two features (Dinner for Monsters and Slit). Samantha/Nurse Nasty is frustrated with how the show is being run by its womanizing director and its drunk and crazy host, Dr. Nasty.

Lydia is an overweight sales clerk in a trendy home furnishings store, nearing 30. Though she is a member of a Fat Acceptance Group (a movement dedicated to fighting prejudice against overweight people), she is still struggling with complex feelings about her body and its place in the world. Darcy, a recovering-anorexic real estate agent in her mid-20s, is struggling with the same issues from a very different perspective.